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The Callisto Protocol's new trailer has a simple message: Kill fast or die ugly

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Striking Distance Studios boss Glen Schofield made at appearance at today's Opening Night Live showcase for Gamescom to show off some fresh gameplay from the upcoming horror game The Callisto Protocol (opens in new tab), and its new system of mutations that will enable enemies to transform into "bigger, badder, faster meaner" opponents if they're not killed quickly.

It's a subtle effect, and the trailer moves pretty quickly, but you can see see the enemies transforming during the fight, sprouting tentacles and even regrowing a skull after it's blown off in appropriately gory fashion. It seems pretty clear that at least some enemies will need to be taken down in a hurry if you want to avoid a prolonged fight, and the suffering that invariably arises from such encounters.

It all ends badly, though, as Callisto Protocol trailers so often do: After an extended ride through a torrent of what I can only assume is untreated sewage and sticky viscera, our hero zigs when he really, really should have zagged. Bad move, bud.

The Callisto Protocol is set to come out on December 2.

Catch up with our full list of Gamescom announcements from Opening Night Live and check our Gamescom schedule to find out when to watch everything else.

Andy has been gaming on PCs from the very beginning, starting as a youngster with text adventures and primitive action games on a cassette-based TRS80. From there he graduated to the glory days of Sierra Online adventures and Microprose sims, ran a local BBS, learned how to build PCs, and developed a longstanding love of RPGs, immersive sims, and shooters. He began writing videogame news in 2007 for The Escapist and somehow managed to avoid getting fired until 2014, when he joined the storied ranks of PC Gamer. He covers all aspects of the industry, from new game announcements and patch notes to legal disputes, Twitch beefs, esports, and Henry Cavill. Lots of Henry Cavill.